Imaging Initiative

Molecular Imaging of the inflammatory-fibrosis axis in LV remodeling.

The goals of the Preclinical imaging studies are to integrate the use of CCR2 and FAP PET probes to answer mechanistic questions posed in Q1, Q2, and the therapeutic initiative. Proof of concept human imaging studies will provide key information on the relevance of the IMMUNO-FIB axis in post-myocardial infarction (MI) patient population.
The goals of the Preclinical imaging studies are to integrate the use of CCR2 and FAP PET probes to answer mechanistic questions posed in Q1, Q2, and the therapeutic initiative. Proof of concept human imaging studies will provide key information on the relevance of the IMMUNO-FIB axis in post-myocardial infarction (MI) patient population.

“We envision that molecular imaging will offer unprecedented insights into the natural history of cardiac inflammation and fibrosis, enhance crosstalk between bench and bedside, provide paradigm-shifting diagnostic tools to assign patient prognosis, and safely enable precise implementation of therapeutics targeting the inflammatory-fibrosis axis.”

Dr. Robert Gropler, Washington University School of Medicine, Lead Coordinator- Imaging Initiative

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